Informational only — Not medical advice. Always consult a licensed healthcare provider.

Community data Updated 2 months ago

Indications

Indoseem is used to relieve the pain and inflammation of rheumatoid arthritis, ankylosing spondylitis, osteoarthritis (degenerative joint disease), and gout, as well as acute non-articular rheumatic conditions such as bursitis, synovitis, and tendinitis.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Indomethacin is an NSAID with pain-relieving and fever-reducing effects. Clinical and pharmacological studies have confirmed that it has strong anti-inflammatory, analgesic, and antipyretic action. Unlike corticosteroids, its effect does not depend on the pituitary gland or the adrenal glands. Taken by mouth, it is absorbed quickly, with peak blood levels reached within about 2 hours. Roughly two-thirds of the drug is passed out in the urine and the rest in the stool, with about 90% of a single dose cleared from the body within 24 to 48 hours. In controlled clinical trials, Indomethacin has shown real benefit in treating rheumatic conditions, easing pain, reducing joint swelling, and improving joint movement.

Pregnancy & Breastfeeding

Not recommended during pregnancy, as there isn't yet enough clinical evidence to confirm it's safe.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: 75 mg sustained-release capsule: Rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis (degenerative joint disease): The initial dose is 75 mg sustained-release capsule once daily. If severe then twice daily is required. Acute attacks of gout: May control with a dose of 75 mg sustained-release capsule twice daily. Acute non-articular rheumatism (bursitis, synovitis, tendinitis): 1-2 sustained-release capsule daily according to the severity of this case. 25 mg capsule: Rheumatic diseases: 50-200 mg daily in divided doses Acute gout: 150-200 mg daily in divided doses Dysmenorrhea: up to 75 mg daily 

Side Effects & Interactions