Informational only — Not medical advice. Always consult a licensed healthcare provider.

MedBD
বাং
Community data Updated 2 months ago

Halobetasol Propionate

Other Topical corticosteroids Prescription
Check interactions
🌐 বাংলায় দেখুন

Indications

Psoriasis

Halobetasol Propionate 0.05% cream or ointment is a super-high potent corticosteroid used to relieve the inflammation and itching seen in dermatoses that respond to corticosteroid treatment. It should not be used beyond two consecutive weeks, and the total amount used should not exceed 50 gm per week, because of the potential for the drug to suppress the Hypothalamic-Pituitary-Adrenal (HPA) axis. The 0.01% lotion is likewise a super-high potent corticosteroid used to relieve the inflammation and itching of corticosteroid-responsive dermatoses, including plaque psoriasis, and it may be used continuously for up to 8 weeks.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Like other topical corticosteroids, halobetasol propionate works through anti-inflammatory, antipruritic and vasoconstrictive actions. The exact mechanism behind the anti-inflammatory effect of topical corticosteroids in general is still not fully understood. However, it is believed that corticosteroids act by inducing phospholipase A2 inhibitory proteins, known collectively as lipocortins. These proteins are thought to regulate the production of powerful inflammatory mediators such as prostaglandins and leukotrienes by blocking the release of their shared precursor, arachidonic acid. Arachidonic acid itself is released from membrane phospholipids through the action of phospholipase A2.

Pregnancy & Breastfeeding

Topical corticosteroids should be used in pregnancy only when the expected benefit outweighs any possible risk to the unborn baby. It is also not known whether using this medicine on the skin leads to enough absorption into the bloodstream to appear in breast milk. For this reason, it should be used with caution by breastfeeding mothers.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: 0.05% Halobetasol Propionate: Apply a thin layer of Halobetasol Cream or Ointment to the affected skin once or twice daily, as directed by the physician, and rub in gently and completely. Halobetasol 0.05% is a super-high potency corticosteroid; therefore, treatment should be limited to two weeks, and amounts greater than 50 gm/week should not be used. As with other highly active corticosteroids, therapy should be discontinued when control has been achieved. If no improvement is seen within 2 weeks, reassessment of the diagnosis may be necessary. Halobetasol should not be used with occlusive dressings.0.01% Halobetasol Propionate: Apply a thin layer of Halobetasol Propionate Lotion to affected areas once daily. Rub in gently. Wash hands after each application, unless Halobetasol Propionate Lotion is for treatment of the hands. This Lotion treatment beyond 8 weeks is not recommended, and the total dosage should not exceed approximately 50 g per week. Discontinue treatment if control is achieved before 8 weeks. Do not use with occlusive dressings unless directed by a physician. This Lotion should not be used on the face, groin, or in the axillae. This Lotion is not for oral, ophthalmic, or intravaginal use.