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Community data Updated 2 months ago
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Indications

Hyperlipidemia

Lesterol is an HMG-CoA reductase inhibitor (statin) indicated as an adjunctive therapy to diet to: Reduce elevated TC, LDL-C, Apo B, and TG, and to increase HDL-C in adult patients with primary hypercholesterolemia and mixed dyslipidemia  Reduce elevated TC, LDL-C, and Apo B levels in boys and post-menarchal girls, 10 to 16 years of age, with heterozygous familial hypercholesterolemia after failing an adequate trial of diet therapy ... Read moreLesterol is an HMG-CoA reductase inhibitor (statin) indicated as an adjunctive therapy to diet to: Reduce elevated TC, LDL-C, Apo B, and TG, and to increase HDL-C in adult patients with primary hypercholesterolemia and mixed dyslipidemia  Reduce elevated TC, LDL-C, and Apo B levels in boys and post-menarchal girls, 10 to 16 years of age, with heterozygous familial hypercholesterolemia after failing an adequate trial of diet therapy Reduce the risk of undergoing revascularization procedures in patients with clinically evident CHD Slow the progression of atherosclerosis in patients with CHD.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Fluvastatin works by competitively blocking HMG-CoA reductase, the enzyme responsible for cholesterol production. This lowers plasma levels of total cholesterol, triglycerides, LDL, and VLDL, while raising HDL levels.

Pregnancy & Breastfeeding

Pregnancy: Fluvastatin must not be used by women who are pregnant or who may become pregnant. During a normal pregnancy, blood cholesterol and triglyceride levels rise naturally, and cholesterol (or substances derived from it) is essential for the developing baby. Because of this, Fluvastatin can potentially harm the fetus if taken during pregnancy. Since hardening of the arteries (atherosclerosis) develops slowly over many years, briefly stopping cholesterol-lowering treatment during pregnancy is unlikely to affect the long-term management of high cholesterol. Fluvastatin should only be given to women of childbearing age if pregnancy is highly unlikely, and only after they have been made aware of the possible risks. If a patient becomes pregnant while taking this medicine, it should be stopped right away and she should be informed of the potential risk to her unborn child.

Breastfeeding: Fluvastatin passes into breast milk in animal studies, and because this class of medicines (HMG-CoA reductase inhibitors) can potentially cause serious side effects in nursing infants, mothers who need Fluvastatin treatment should not breastfeed.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: General Dosing Information: Fluvastatin is taken by mouth in doses ranging from 20 mg to 80 mg per day, as a single dose, with or without food. Capsules should not be broken, crushed, chewed or opened before use, and two 40 mg Fluvastatin capsules should not be taken at the same time. Because a given dose reaches its full effect within about 4 weeks, lipid levels should be checked again at that point and the dose adjusted based on how the patient responds and on established treatment guidelines. Adult Patients with Hypercholesterolemia (Heterozygous Familial and Nonfamilial) and Mixed Dyslipidemia: The recommended starting dose is one 40 mg Fluvastatin capsule in the evening, or one 40 mg capsule twice a day; two 40 mg capsules should not be taken at the same time. Alternatively, the recommended starting dose is one 80 mg dose taken once, at any time of day. Pediatric Patients (10 to 16 years of age) with Heterozygous Familial Hypercholesterolemia: The recommended starting dose is one 20 mg Fluvastatin capsule. Any increase in dose, up to a maximum of 40 mg twice daily or 80 mg once daily, should be made at intervals of 6 weeks, with the dose tailored to the individual patient's treatment goals.

Side Effects & Interactions

Side Effects

No side-effect data recorded yet.