Informational only — Not medical advice. Always consult a licensed healthcare provider.

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Community data Updated 2 months ago
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Indications

Cancer

Proscan Tablets are indicated for use together with LHRH agonist analogues (such as leuprolide acetate) to treat metastatic prostatic carcinoma (stage D2). To gain the full benefit of this combined therapy, treatment with both drugs must be started at the same time. Proscan Tablets are also indicated as adjunctive therapy following orchiectomy, to help achieve complete androgen blockade. Combined with LHRH agonists, Proscan Tablets are indicated as well before and during definitive external beam radiotherapy in patients with bulky, locally advanced Stage B2 and Stage C prostatic carcinoma.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Prostatic carcinoma is known to respond to treatments that counteract the effect of androgen or remove its source (e.g., castration), since it is androgen-sensitive. Studies in animals have shown that flutamide is a potent antiandrogen: it works either by blocking the uptake of androgen, by blocking androgen from binding within the nucleus of cells in target tissues, or through both mechanisms together.

Pregnancy & Breastfeeding

Studies haven't been done in pregnant or breastfeeding women, so it isn't known for certain whether Flutamide could harm an unborn baby or pass into breast milk. Because this hasn't been ruled out, it should be assumed possible, and the medicine should be used with appropriate caution in these situations.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Recommended Adult Dosage Flutamide is generally prescribed as one 250 mg tablet taken three times a day, spaced eight hours apart, whether it is used alongside surgical removal of the testicles (orchiectomy) or together with an LHRH agonist injection. When paired with an LHRH agonist, the two treatments can either be started on the same day, or Flutamide can be started a day (24 hours) beforehand. For bulky, locally advanced prostate cancer (Stage B2 and Stage C), the same dosing schedule applies: one 250 mg tablet, three times daily at eight-hour intervals, with Flutamide again started either at the same time as the LHRH agonist or a day earlier. When Flutamide is used alongside external beam radiation therapy, it is typically started eight weeks before radiation begins and continued for the entire course of treatment.

Side Effects & Interactions

Side Effects

No side-effect data recorded yet.

Key Interactions

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