Indications
Pain and inflammation caused by rheumatic disease and other musculoskeletal disorders such as rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, frozen shoulder, and low back pain, as well as sprains and strains. It is also used for mild to moderate pain, including period pain (dysmenorrhoea), migraine, pain after surgery, dental pain, and for relieving a sore throat.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Flurbiprofen is a cyclooxygenase inhibitor with potent anti-inflammatory effects, along with antipyretic and analgesic activity. It inhibits the biosynthesis of prostaglandin and thromboxane, blocks vasodilatation, and prevents the sensitization of pain fibers by prostaglandins.
Flurbiprofen is readily absorbed (more than 95%) after oral administration, reaching peak serum concentration at about 1.5 hours, with an apparent half life of 2 to 6 hours. It is extensively protein bound (99%), and the amount absorbed does not differ significantly whether it is taken before or after food. About 95% of a dose is excreted in the urine within 24 hours, with small amounts also excreted in breast milk. There is no evidence that the drug accumulates in the body.
Pregnancy & Breastfeeding
Flurbiprofen's safety in pregnancy has not been established. It is not contraindicated while breastfeeding, but its safety there is also unproven.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.