Informational only — Not medical advice. Always consult a licensed healthcare provider.

Community data Updated 2 months ago

Indications

Zactrol contains famotidine and is used to treat gastric ulcer, duodenal ulcer, anastomotic ulcer, and acute stress ulcer, as well as reflux esophagitis and Zollinger-Ellison syndrome. It is also used to treat acute gastritis and flare-ups of chronic gastritis.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Famotidine belongs to a class of medicines called H2-receptor antagonists. It works by completely blocking the action of histamine on the H2-receptors found in the acid-producing cells of the stomach lining. Through this action, it reduces acid secretion that would otherwise occur at baseline, overnight, and in response to pentagastrin stimulation. Because famotidine separates only slowly from these H2-receptors once bound, its acid-suppressing effect also wears off gradually rather than stopping abruptly.

Pregnancy & Breastfeeding

Pregnancy category B. There are no adequate and well-controlled studies in pregnant women. This drug should be used during pregnancy only if clearly needed. Caution should be exercised when Famotid is administered to a nursing woman.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Tablet: For gastric ulcer, duodenal ulcer, anastomotic ulcer, upper gastro-intestinal hemorrhage, reflux esophagitis and Zollinger-Ellison syndrome: Usual dose for adults: Famotidine 20 mg twice daily (after breakfast and after supper or before bed time) or Famotidine 40 mg can be administered orally once daily at bed time. For the treatment of acute gastritis, chronic gastritis in acute exacerbation stage: Usual dosage for adults is Famotidine 20 mg orally twice a day (after breakfast and after supper or before bed time). Also Famotidine 40 mg can be orally administered once a day (before bed time), dosage should be adjusted according to age and symptoms. Most ulcer patients heal within 4-8 weeks. For maintenance therapy the recommended oral dose is 20 mg once daily. Or, as directed by the registered physician. Powder for Suspension:Gastroesophageal Reflux Disease(GERD): <1 year of age: 0.5 mg/kg/dose of famotidine oral suspension up to 8 weeks once daily in patients Age 3 to 11 months: 0.5 mg/kg/dose twice daily up to 8 weeks Age 1 to 2 months: 0.5 mg/kg/dose once daily up to 8 weeks Neonates: 0.5 mg/kg/dose maximum once daily up to 8 weeks Patients 1-16 years of age: Gastroesophageal Reflux Disease(GERD): 1 mg/kg/day p.o. divided b.i.d. up to 40 mg b.i.d. Duodonal ulcer: 0.5 mg/kg/day p.o. at bedtime or divided b.i.d. up to 40 mg/day. Peptic ulcer: 0.5 mg/kg/day p.o. at bedtime or divided b.i.d. up to 40 mg/day. Maintenance therapy: 40 mg at daily night. Reflux esophagitis: 2 mg/kg/day Zollinger-Ellison Syndrome: 40 mg 3 times daily.

Side Effects & Interactions

Side Effects

No side-effect data recorded yet.