Indications
Panodin SR is used for both short-term and ongoing relief of osteoarthritis and rheumatoid arthritis, for easing acute pain, and for treating acute gout.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Similar to other NSAIDs, etodolac's anti-inflammatory action comes from blocking the enzyme cyclooxygenase (COX), which reduces the production of prostaglandins in body tissues that help drive inflammation. It works by attaching to the upper part of the COX active site, blocking its substrate, arachidonic acid, from reaching that site. Etodolac was once considered a non-selective COX inhibitor, but is now recognized as being 5 to 50 times more selective for COX-2 than COX-1. Its fever-reducing effect is thought to arise from action on the hypothalamus in the brain, which widens peripheral blood vessels, boosts blood flow to the skin, and allows heat to escape the body.
Pregnancy & Breastfeeding
Pregnancy & Breastfeeding: There haven't been enough well-controlled studies looking at Etodolac's safety in pregnant women, so it should only be used during pregnancy if the potential benefit to the mother is thought to outweigh the possible risk to the unborn baby. It also isn't known whether Etodolac passes into breast milk, so a nursing mother and her doctor should weigh how important the medicine is to her health when deciding whether to continue breastfeeding or continue the treatment.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.