Indications
Span is used to relieve smooth-muscle spasm affecting the stomach, intestines, or pylorus, as well as in gallstone disease (cholelithiasis) and spastic constipation. It also eases the painful straining of dysentery (tenesmus), menstrual cramps (dysmenorrhoea), and peripheral vascular disorders. Because it does not carry cardiotoxic or blood-pressure-lowering effects, Span is also of particular value in managing coronary insufficiency and angina pectoris.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Drotaverine HCl is a newer, highly potent synthetic antispasmodic that the body absorbs readily from the intestine. Like papaverine, it acts directly on smooth muscle fibers, but its antispasmodic effect surpasses that of standard preparations. Drotaverine HCl is notable for its fast onset of action, which makes it especially useful in acute, painful spastic conditions. Besides its spasmolytic and vasodilatory effects, Drotaverine HCl also produces a selective blockade of cardiac beta-receptors.
Pregnancy & Breastfeeding
No teratogenic effects have been seen in animal studies, but drotaverine should still be avoided during pregnancy and breastfeeding.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.