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Diclofenac Sodium

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Indications

Pain Osteoarthritis Gout Menstrual Disorder Inflammation

Voltafen is indicated in-Rheumatology: Inflammatory and degenerative forms of rheumatism, chronic involutive, polyarthritis, ankylosing spondylarthritis, osteoarthritis, spondylarthroses, acute gout, peri-articular rheumatic disorders.Surgery and Traumatology ... Read moreVoltafen is indicated in-Rheumatology: Inflammatory and degenerative forms of rheumatism, chronic involutive, polyarthritis, ankylosing spondylarthritis, osteoarthritis, spondylarthroses, acute gout, peri-articular rheumatic disorders.Surgery and Traumatology: Sprain, bruises, dislocations, fractures, softtissue injuries, surgical interventions.Obstetrics and Gynecology: Primary dysmenorrhoea, episiotomy, adnexitis, endometritis, parametritis, salpingitis, and mastitis.Otorhinolaryngology: As pre-operative medication for the prevention of pain, inflammation, and swelling.Dentistry: Post-operative and post-traumatic pain, inflammation, and swelling.Other indications: For the prevention of pain and treatment of inflammation and swelling of patients operated in the urogenital tract, renal and biliary colic.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Diclofenac Sodium is a powerful non-steroidal anti-inflammatory drug (NSAID), valued for its strong anti-rheumatic, anti-inflammatory, analgesic and antipyretic effects, along with some uricosuric activity. It works by inhibiting prostaglandin biosynthesis, the process largely responsible for inflammation, pain and fever.

When taken with or after food, Diclofenac is absorbed rapidly and completely from the gastro-intestinal tract, reaching peak plasma concentrations on average within 2 hours. At therapeutic levels, it is 99.7% bound to plasma proteins. The drug is metabolized in the liver and undergoes first-pass metabolism.

Pregnancy & Breastfeeding

During pregnancy, Diclofenac should only be used when there is a compelling reason to do so, and at the lowest effective dose. It is not recommended during the first trimester. Because clinical data are insufficient, Diclofenac Sodium Gel is also not recommended for use during pregnancy. Only a very small amount of Diclofenac passes into breast milk, and no harmful effects on the infant are expected.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Diclofenac FC Tablet: Adults take 75 to 150 mg a day in 2 to 3 divided doses, preferably after food. The dose should be reduced for long term use. Diclofenac SR Tablet: Adults take 1 tablet daily, swallowed whole with liquid, preferably at meal times. If needed, the daily dose can be raised to 150 mg by adding conventional tablets. For children, the dose is 1 to 3 mg of diclofenac per kg of body weight daily in divided doses. In elderly or debilitated patients, the lowest effective dose is recommended, although the pharmacokinetics of diclofenac sodium is not affected to any clinically relevant extent by age. Diclofenac Dispersible Tablet: Adults are recommended 2 to 3 tablets daily, with a maximum daily dose of 150 mg. In milder cases, 2 tablets of Diclofenac DT a day are enough. Diclofenac DT should preferably be taken before meals. It is not recommended for children for other indications except juvenile rheumatoid arthritis, where the recommended dose is 1 to 3 mg per kg of body weight. Diclofenac DT should be dropped into a half glass of water and the liquid stirred to help it disperse before it is swallowed. There is no information on using Diclofenac DT for more than 03 months. Diclofenac TR Capsule: One capsule daily, preferably taken after mealtimes. Diclofenac Suppository: Adults take a 50 mg suppository 2 to 3 times daily, with a maximum daily dose of 150 mg. Diclofenac Injection: The usual adult dose is 1 ampoule daily. In serious cases, this may be increased to up to 2 ampoules daily. Diclofenac Gel: For external use only. Depending on the size of the area being treated, 2 to 4 g of Diclofenac gel should be applied to the skin 3 to 4 times daily and rubbed in lightly over the affected area. This gel may also be used alongside treatment with other dosage forms of Diclofenac.

Side Effects & Interactions

Side Effects

No side-effect data recorded yet.