Indications
Chronic dry, unproductive coughs, as well as acute dry coughs disrupting normal function or sleep, may be treated with dextromethorphan.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Dextromethorphan Hydrobromide is a cough suppressant that acts centrally on the cough centre in the medulla. Although it is structurally related to morphine, it has no analgesic properties and generally shows little sedative activity. No addiction has been observed even after fairly large doses are given over a prolonged period. It is absorbed quickly from the GI tract, taking effect within 15 to 30 minutes of oral administration, and its action lasts about 3 to 6 hours in conventional dosage form. The drug is extensively metabolised in the liver and is excreted in the urine both unchanged and as demethylated metabolites, including Dextrophan, which itself has some cough-suppressant activity. Together, the parent drug and its metabolites account for up to 50% of the ingested dose excreted in the urine over 24 hours, with about 8% excreted unchanged within the first 6 hours.
Pregnancy & Breastfeeding
Pregnancy: There isn't much information on using this medicine during pregnancy, so it's best avoided in the first three months.
Breastfeeding: It isn't known whether dextromethorphan passes into breast milk, so breastfeeding mothers are advised not to use it.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.