Indications
Desotop gel is used to treat mild to moderate atopic dermatitis (eczema) in patients aged 3 months and older.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Desonide Gel contains desonide, a synthetic, nonfluorinated corticosteroid used on the skin. Like other topical corticosteroids, it works by reducing inflammation, easing itching and narrowing blood vessels in the treated area. The exact way topical steroids control inflammation is not fully understood, but they are believed to trigger the production of proteins called lipocortins, which block an enzyme (phospholipase A2) that would otherwise release arachidonic acid from cell membranes. Since arachidonic acid is the raw material the body uses to make inflammatory substances such as prostaglandins and leukotrienes, blocking its release is thought to be the key step in reducing inflammation. Once desonide is absorbed through the skin, the body processes it through the same pathways it uses for corticosteroids taken systemically.
Pregnancy & Breastfeeding
Pregnancy Category C. Well-controlled studies in pregnant women are lacking, so Desonide gel should be used in pregnancy only if the potential benefit to the mother outweighs the potential risk to the fetus. Corticosteroids taken systemically pass into human breast milk and may slow infant growth, interfere with the body's own corticosteroid production, or cause other adverse effects. Whether topical corticosteroids are absorbed into the bloodstream in amounts large enough to appear in breast milk is not known. For this reason, Desonide gel should be used with caution in breastfeeding mothers.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.