Indications
Cinnarizine is mainly used to relieve nausea and vertigo caused by Meniere's disease and other inner-ear (labyrinthine) disturbances, and to prevent and treat motion sickness. It is also used to manage various vascular disorders, including disorders of the cerebral circulation.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Cinnarizine acts as an antihistamine, a labyrinthine sedative and a peripheral antivasoconstrictor. It is a selective calcium antagonist that inhibits the intracellular influx of Ca2+. By blocking Ca2+ influx through smooth muscle calcium channels, it prevents Ca2+-dependent contraction of arterial smooth muscle, thereby improving vestibular symptoms and preventing peripheral arterial disease.
Pregnancy & Breastfeeding
Cinnarizine hasn't been thoroughly studied in pregnant women, so its safety during human pregnancy isn't firmly established, even though animal studies haven't shown it to cause birth defects. Given this uncertainty, Cinnarizine is not recommended for use during pregnancy.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.