Informational only — Not medical advice. Always consult a licensed healthcare provider.

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Community data Updated 2 months ago
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Indications

Fungal Infection Inflammation

Candirox Cream is used to treat fungal skin infections such as tinea pedis, tinea cruris, and tinea corporis caused by Trichophyton rubrum, Trichophyton mentagrophytes, Epidermophyton floccosum, and Microsporum canis; candidiasis (moniliasis) caused by Candida albicans; and tinea (pityriasis) versicolor caused by Malassezia furfur. It is also effective against certain gram-negative and gram-positive bacteria. Because of its anti-inflammatory action, Candirox alone is usually enough to treat mild to moderate inflammatory fungal infections.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Ciclopirox Olamine is a synthetic antifungal agent that acts against a broad range of pathogenic dermatophytes, yeasts, and Malassezia furfur, slowing or stopping their growth. In laboratory testing it has shown fungicidal activity against isolates of Trichophyton rubrum, Trichophyton mentagrophytes, Epidermophyton floccosum, Microsporum canis, and Candida albicans. Its mode of action has been studied mainly in Candida albicans. It is thought that Ciclopirox Olamine inhibits or kills fungal cells mainly by depleting certain essential substrates and ions within the cell, an effect brought about by blocking their uptake from the surrounding medium.

Beyond its antifungal action, Ciclopirox also has antibacterial activity against many Gram-positive and Gram-negative bacteria. Its anti-inflammatory effects have been demonstrated in human polymorphonuclear cells, where it inhibits the synthesis of prostaglandin and leukotriene. Ciclopirox can also produce anti-inflammatory effects by inhibiting the formation of 5-lipoxygenase and cyclooxygenase.

Pregnancy & Breastfeeding

Pregnancy Category B. It is not known whether this medicine passes into human breast milk. Since many medicines do pass into breast milk, Ciclopirox Olamine cream should be used with caution in breastfeeding women.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Ciclopirox Cream should be massaged gently into the affected skin and the surrounding area twice a day for four weeks. Most patients notice relief from itching and other symptoms within the first week of starting treatment. If there is no improvement after four weeks of use, the diagnosis should be reviewed. In Tinea versicolor, the infection typically clears both clinically and on fungal testing within two weeks of treatment. Use in children: Safety and effectiveness in children under 10 years of age have not been established.