Informational only — Not medical advice. Always consult a licensed healthcare provider.

MedBD
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Community data Updated 2 months ago
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Indications

Chronic Obstructive Pulmonary Disease Bronchitis Sinusitis Pharyngitis Tonsillitis Bacterial Infection Urinary Tract Infection Respiratory Tract Infection Skin and Soft Tissue Infection Otitis Media

Cephalor treats infections caused by susceptible organisms across several sites in the body. For respiratory tract infections, it is used for acute and chronic bronchitis and infected bronchiectasis. For genito-urinary tract infections, it covers acute and chronic nephritis, cystitis, urethritis, and prostatitis, and it can also be used to prevent recurrent urinary tract infections. For skin and soft tissue infections, it is used when these are caused by staphylococci and/or streptococci. For ear, nose and throat infections, it is indicated for otitis media, mastoiditis, sinusitis, follicular tonsillitis, and pharyngitis. For bone infections, it is used when these are caused by staphylococci and/or P. mirabilis.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Cephalexin is a semisynthetic analogue of Cephalosporin C. It kills bacteria by interfering with the synthesis of the bacterial cell wall. Peptidoglycan is a heteropolymeric structure that gives the cell wall its mechanical stability. In the final stage of peptidoglycan synthesis, cross-linking is completed as the terminal glycine residue of the pentaglycine bridge is linked to the fourth residue of the pentapeptide (d-alanine). The transpeptidase enzyme that carries out this step is inhibited by penicillins and cephalosporins. This weakens the bacterial cell wall, causing the cell to swell and eventually rupture. Cephalexin is a first generation cephalosporin that is active when taken by mouth.

Pregnancy & Breastfeeding

Pregnancy Category B. Cefalexin can be used in pregnancy when your doctor feels it is clearly needed. It also passes into breast milk, so it should be used with caution in nursing mothers.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Adult: The usual dose is 250 mg to 500 mg every 6 hours. For skin and soft tissue infections, streptococcal pharyngitis and uncomplicated cystitis, in patients over 15 years of age, 500 mg of the drug may be given every 12 hours. In severe or deep seated infections the dose can be increased up to 3 g to 6 g daily. Children: The dosage range is 25 to 100 mg/kg/day in divided doses, up to a maximum of 4 g daily. Recommended dose by children's weight: for 10 kg (22 lbs), 62.5 mg to 125 mg four times daily, or 125 mg to 250 mg twice daily. For 20 kg (44 lbs), 125 mg to 250 mg four times daily, or 250 mg to 500 mg twice daily. For 40 kg (88 lbs), 250 mg to 500 mg four times daily, or 500 mg to 1 g twice daily. For streptococcal pharyngitis, skin and soft tissue infections, and in patients over 1 year of age, the total daily dose may be divided and given every 12 hours. In the treatment of otitis media, 75 to 100 mg/kg/day in four divided doses may be required. In the treatment of beta haemolytic streptococcal infections, the therapeutic dose of the drug should be given for at least 10 days.

Side Effects & Interactions

Side Effects

No side-effect data recorded yet.