Indications
Carbiroid is used to treat an overactive thyroid, including thyrotoxicosis and thyroid storm, and it is also given to prepare patients for thyroid surgery. It may likewise be used alongside radioactive ablative therapy.
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Carbimazole belongs to the anti-thyroid class of medicines. It works by lowering the amount of thyroid hormone the body produces. It does this mainly by cutting down the formation of di-iodotyrosine and thyroxine, and to a lesser extent by reducing how much inorganic iodine the thyroid gland takes up and holds onto.
After being taken by mouth, carbimazole is absorbed quickly from the gut and spreads throughout the body. It is entirely converted in the body into methimazole, and it is this metabolite that actually produces the drug's therapeutic effect. Carbimazole crosses the placenta easily and also passes into breast milk in significant amounts, which is worth bearing in mind for pregnant or breastfeeding patients.
Pregnancy & Breastfeeding
Carbimazole can be used during pregnancy in patients with thyrotoxicosis, but it should be given at the lowest dose that keeps the condition controlled, since taking too much can harm the developing baby. The drug also crosses the placenta and passes into breast milk, so it may lead to an underactive thyroid or goitre in the foetus or newborn.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.