Community data Updated 2 months ago

Candesartan Cilexetil

Angiotensin-ll receptor blocker Prescription

Indications

Hypertension Heart Failure

Giran is used to treat high blood pressure (hypertension) and heart failure in which the left ventricle does not pump properly.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Candesartan Cilexetil is an ester prodrug that is hydrolysed to its active form, Candesartan, during absorption from the gastrointestinal tract. Candesartan is an angiotensin II receptor (type AT1) antagonist. It blocks the vasoconstrictor and aldosterone secreting effects of angiotensin II by selectively blocking the binding of angiotensin II to the AT1 receptor in many tissues, such as vascular smooth muscle and the adrenal gland.

Pregnancy & Breastfeeding

Discontinue Candesartan Cilexetil as soon as pregnancy is confirmed. The medicine may be used while breastfeeding.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Hypertension: Start with 8 mg once daily. In hepatic impairment, start with 2 mg; in renal impairment or intravascular volume depletion, start with 4 mg. If necessary, the dose may be increased at intervals of 4 weeks, up to a maximum of 32 mg once daily. The usual maintenance dose is 8 mg once daily. Heart failure: Start with 4 mg once daily. The dose may be increased at intervals of at least 2 weeks, up to the target dose of 32 mg once daily or the maximum tolerated dose.

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Candesartan Cilexetil

Indications

Pharmacology

Pregnancy & Breastfeeding

Dosage Reference

Side Effects & Interactions

Side Effects

Key Interactions