Calcium Acetate

Calcium Acetate binds with dietary phosphate when taken with meals, forming insoluble calcium phosphate that is then passed out in the stool. Keeping serum phosphorus below 6.0 mg/dl is generally regarded as a clinically acceptable treatment outcome with phosphate binders. Because Calcium Acetate is highly soluble at neutral pH, the calcium it releases is readily available to bind phosphate in the proximal small intestine. Studies of oral Calcium Acetate pharmaceutical formulations show systemic absorption of up to about 40% when taken on an empty stomach and up to about 30% when taken with food, based on data from both healthy subjects and renal dialysis patients under various conditions.