Informational only — Not medical advice. Always consult a licensed healthcare provider.

MedBD
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Community data Updated 2 months ago
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Indications

Osteoporosis

Improcal is indicated for post-menopausal osteoporosis, renal osteodystrophy, postsurgical hypoparathyroidism, idiopathic hypoparathyroidism, pseudohypoparathyroidism, secondary hyperparathyroidism in patients with moderate to severe chronic renal failure (pre-dialysis), and vitamin D dependent rickets.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Calcitriol is one of the most important active forms of vitamin D3. It is normally produced in the kidneys from its precursor, 25-hydroxycholecalciferol. Calcitriol helps the intestines absorb calcium and helps regulate how bone tissue is mineralized. Its key role is maintaining calcium balance in the body, which includes stimulating osteoblast activity (the bone-building cells) in the skeleton.

Pregnancy & Breastfeeding

Calcitriol, a vitamin used in bone formation, has not been shown to cause birth defects in humans. Even so, it should be used in pregnancy only if the expected benefit to the mother justifies the possible risk to the unborn baby. Breastfeeding mothers may continue taking Calcitriol, but calcium levels in both the mother's and the baby's blood should be monitored while doing so.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: The optimal daily dose of Calcitriol capsule must be carefully determined for each patient on the basis of serum calcium level. In Post-menopausal Osteoporosis: The recommended dose of Calcitriol capsule is 0.25 mcg twice daily. In Renal Osteodystrophy (dialysis patients): The initial daily dose is 0.25 mcg of Calcitriol capsule. In patients with normal or only slightly reduced calcium levels, doses of 0.25 mcg every other day are sufficient. In Hypoparathyroidism and Rickets: The recommended initial dosage of Calcitriol capsule is 0.25 mcg per day, given in the morning. If a satisfactory response is not observed within 2 to 4 weeks on the usual dose, the dose may be increased at intervals of 2 to 4 weeks. The recommended intravenous initial dose of Calcitriol injection, depending on the severity of the hypocalcemia and/or secondary hyperparathyroidism, is 1 mcg (0.02 mcg/kg) to 2 mcg, administered three times weekly, at intervals of approximately every other day. Doses as small as 0.5 mcg and as large as 4 mcg three times weekly have been used as an initial dose. If a satisfactory response is not observed, the dose may be increased by 0.5 to 1 mcg at intervals of two to four weeks.

Side Effects & Interactions

Side Effects

No side-effect data recorded yet.