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Community data Updated 2 months ago

Almotriptan

5-HT Agonists Prescription
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Indications

Migraine Headache

Almitan is used to relieve the acute headache phase of a migraine attack, whether or not it is accompanied by aura. It is also notable as the only oral triptan approved in the USA for treating migraine in adolescents aged 12 to 17 years.

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Almotriptan is a selective, potent agonist of serotonin (5-hydroxytryptamine 1B/1D) receptors. By binding to these receptor sites on the meningeal arteries, it blocks the release of vasoactive peptides and prompts the arteries to constrict. Its action on arteries supplying the brain is limited, and it has little effect on blood vessels in the heart and lungs.

Pregnancy & Breastfeeding

Pregnancy Category C. It is not known whether almotriptan passes into human breast milk.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Acute Treatment of Migraine Attacks: For adults and adolescents aged 12 to 17, the recommended dose of Almotriptan is 6.25 mg to 12.5 mg, and in adults the 12.5 mg dose tends to work better. If the headache eases after the first dose of almotriptan malate but comes back, a second dose may be taken after 2 hours. The total daily dose should not go beyond 25 mg. Treating more than an average of four migraines per 30 days has not been established as safe. Hepatic Impairment: In patients with hepatic impairment, the recommended starting dose of almotriptan malate is 6.25 mg, and the total dose over 24 hours should not go beyond 12.5 mg. Renal Impairment: In patients with severe renal impairment, the recommended starting dose of almotriptan malate is 6.25 mg, and the total dose over 24 hours should not go beyond 12.5 mg.

Side Effects & Interactions

Side Effects

No side-effect data recorded yet.