Alfuzosin Hydrochloride
Indications
Alfasin XR is used to relieve the signs and symptoms of benign prostatic hyperplasia (BPH). It eases lower urinary tract symptoms (LUTS) linked with BPH, such as frequent urination, waking at night to urinate (nocturia), a feeling of incomplete bladder emptying, and difficulty starting to urinate (urinary hesitancy).
⚠️ Always consult a registered physician before taking any medicine.
Pharmacology
Alfuzosin hydrochloride works by selectively blocking post-synaptic α1-adrenoreceptors, which are found in the prostate, bladder base, bladder neck, prostatic capsule, and prostatic urethra. By binding competitively and selectively to these α1-adrenergic receptors in the lower urinary tract, it relaxes smooth muscle tone in the prostate, prostatic capsule, bladder neck, and proximal urethra. It also eases sympathetic nervous stimulation, lowers resting urethral pressure, and inhibits the sympathetic nervous stimulation caused by urethral hypertonia. Because it is uroselective, alfuzosin preferentially targets α1 receptors in the prostate; blocking these receptors reduces BPH symptoms, improves urine flow, and lowers the likelihood of hypertensive events.
Pregnancy & Breastfeeding
Not applicable, as this medicine is used only in men.
⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.
Dosage Reference
⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.
Side Effects & Interactions
Side Effects
No side-effect data recorded yet.