Informational only — Not medical advice. Always consult a licensed healthcare provider.

Community data Updated 2 months ago

Indications

Adapalene cream and gel are used on the skin to treat acne vulgaris (common acne).

⚠️ Always consult a registered physician before taking any medicine.

Pharmacology

Adapalene acts on retinoid receptors that are commonly found in the skin of the face, back, and chest. Biochemical and pharmacological studies have shown that Adapalene modulates cellular differentiation, keratinization, and inflammatory processes, all of which are important features in the pathology of acne vulgaris. Adapalene binds with specific retinoic acid nuclear receptors that normalize the differentiation of follicular epithelial cells, resulting in decreased microcomedone formation. Absorption of Adapalene through human skin is low.

Pregnancy & Breastfeeding

Use Adapalene during pregnancy only if the expected benefit to the mother outweighs any possible risk to the unborn baby. It isn't known whether this medicine passes into breast milk, so it should be used with caution by breastfeeding mothers.

⚠️ Talk to your doctor before taking any medicine during pregnancy or while breastfeeding.

Dosage Reference

⚠️ Reference ranges from official sources only. Consult your doctor for personalized dosing.

Adults: Dosage Adapalene 0.1%: Apply to the affected areas of the skin once daily at night. Adapalene 0.3%: Apply to the entire face and any other affected areas once daily in the evening. Children under 12 years: Safety and effectiveness have not been established for children under 12 years of age.

Side Effects & Interactions

Side Effects

No side-effect data recorded yet.

Key Interactions

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