Ethinyl Estradiol + Gestodene Rifampicin
ModerateRifampicin can make ethinyl estradiol work less well. It can lower the amount of ethinyl estradiol in your blood, and that may weaken the effect of the pill. Rifampicin is one of several medicines known to do this, along with phenytoin, primidone, rifabutin, dexamethasone, griseofulvin, topiramate, some protease inhibitors, modafinil, ritonavir and barbiturates.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.