Drug Interaction Checker

Find out if your medicines are safe to take together.

1 Add each medicine you take: the brand on the box or the medicine inside it.
2 We check every pair, including each ingredient of combination medicines.
3 See what could happen and what to do, in plain language.

Your medicines

Take these together with care

We found interactions that usually need care rather than stopping a medicine. Your doctor may adjust a dose or check on you more often.

3 Moderate 1 pair checked

3 interactions

Rifampicin + Isoniazid + Pyrazinamide + Ethambutol contains Rifampicin Cyclosporine

Moderate

Rifampicin can lower the amount of Cyclosporine in your blood. When the level drops, Cyclosporine may not work as well as it should. This matters most for people who take it to protect a transplanted organ or to control an immune condition. If you need both medicines, your doctor may check your Cyclosporine level and change the dose. Do not change or stop either medicine on your own.

What should I do?

These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.

Rifampicin + Isoniazid + Pyrazinamide + Ethambutol contains Rifampicin + Isoniazid Cyclosporine

Moderate

The rifampicin in this medicine can lower the level of cyclosporine in your blood. With less cyclosporine in the blood, it may not work as well as it should.

What should I do?

These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.

Rifampicin + Isoniazid + Pyrazinamide + Ethambutol Cyclosporine

Moderate

The rifampicin in this combination makes your liver break down certain medicines faster than normal. Cyclosporine is one of them. When the two are taken together, your body clears cyclosporine more quickly, so less of it stays in your blood and it may not work as well as it should.

What should I do?

These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.

Feeling unwell after taking your medicines? For an emergency call 999. For free advice from a doctor, call the 16263 health line (Shasthya Batayon), any time.

What do Major, Moderate and Minor mean?

Major

The combination can cause serious harm or stop a medicine from working. Usually avoided, or only used with close medical supervision.

Moderate

The combination may need care: a different dose, taking them at different times, or extra check-ups.

Minor

Little or no effect is expected. Usually nothing needs to change.

Duplicate

Two of your medicines contain the same ingredient, which can add up to a double dose.

Important: This checker lists interactions found in medicine leaflets and may not be complete. It does not know your dose, your health conditions, or food and supplement interactions. Never start, stop or change a medicine because of this tool alone: ask a registered doctor or pharmacist.