Caspofungin Acetate Rifampicin
ModerateRifampicin is a strong inducer of CYP3A4, a liver enzyme, so taking it with caspofungin is expected to lower the amount of caspofungin in the blood. For that reason, adults on rifampin should get 70 mg of caspofungin daily, and children on rifampin should get 70 mg/m 2 of caspofungin daily, but never more than an actual daily dose of 70 mg.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.