Trilaciclib Dofetilide
ModerateTaking trilaciclib together with dofetilide may raise the amount of dofetilide that builds up in the kidney. This is because trilaciclib can increase the concentration of medicines handled by the OCT2, MATE1 and MATE-2K transporters, and dofetilide is one of them.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.