Ceritinib Rifampicin
ModerateRifampicin (rifampin) is a strong CYP3A4/P-gp inducer, and taking it with ceritinib lowers the amount of ceritinib in your body. This is why strong CYP3A inducers like rifampicin should not be used together with ceritinib.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.