Obeticholic Acid Colesevelam Hydrochloride
ModerateColesevelam is a bile acid binding resin. It works by soaking up bile acids in the gut and stopping them from being absorbed. Obeticholic acid is itself a bile acid, so colesevelam can bind it in the same way. When that happens, less obeticholic acid gets absorbed into the body, its level in the blood may fall, and it may not work as well as it should.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.