Diclofenac Sodium + Misoprostol contains Diclofenac Sodium Warfarin Sodium
MajorNSAIDs increase bleeding risk, particularly GI haemorrhage, and may affect INR.
These medicines can affect each other in a serious way. Do not start taking them together unless your doctor has said it is OK. If you already take both, do not stop either one on your own: speak to your doctor or pharmacist soon.
Clinical management: Avoid combination; use paracetamol if possible.