Drug Interaction Checker

Find out if your medicines are safe to take together.

1 Add each medicine you take: the brand on the box or the medicine inside it.
2 We check every pair, including each ingredient of combination medicines.
3 See what could happen and what to do, in plain language.

Your medicines

Take these together with care

We found interactions that usually need care rather than stopping a medicine. Your doctor may adjust a dose or check on you more often.

1 Moderate 1 pair checked

1 interaction

Aleena Drospirenone St. John's Wort

Moderate

St. John's Wort can make drospirenone-containing birth control pills work less well. Some medicines and herbal products, St. John's Wort among them, switch on certain enzymes in the body, including one called cytochrome P450 3A4 (CYP3A4). These enzymes break down the hormones in hormonal contraceptives (HCs) faster, so less of the hormone stays in your blood. This can lower how well the contraceptive protects you and may cause bleeding between periods (breakthrough bleeding). The leaflet lists efavirenz as another medicine that can reduce how well HCs work.

What should I do?

These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.

Feeling unwell after taking your medicines? For an emergency call 999. For free advice from a doctor, call the 16263 health line (Shasthya Batayon), any time.

What do Major, Moderate and Minor mean?

Major

The combination can cause serious harm or stop a medicine from working. Usually avoided, or only used with close medical supervision.

Moderate

The combination may need care: a different dose, taking them at different times, or extra check-ups.

Minor

Little or no effect is expected. Usually nothing needs to change.

Duplicate

Two of your medicines contain the same ingredient, which can add up to a double dose.

Important: This checker lists interactions found in medicine leaflets and may not be complete. It does not know your dose, your health conditions, or food and supplement interactions. Never start, stop or change a medicine because of this tool alone: ask a registered doctor or pharmacist.