Palcigen Palbociclib Saquinavir
MajorSaquinavir is a strong CYP3A inhibitor, which means it slows down the liver enzyme that normally breaks down Palbociclib. If you take the two together, Palbociclib can build up in your body and reach higher levels than intended. That can make its side effects stronger. The leaflet says to avoid taking these two medicines together.
These medicines can affect each other in a serious way. Do not start taking them together unless your doctor has said it is OK. If you already take both, do not stop either one on your own: speak to your doctor or pharmacist soon.