Ventoxen Venetoclax Rifampicin
MajorVenetoclax is carried out of cells by P-gp and BCRP, and rifampicin blocks P-gp. In a study of 11 healthy people, a single 600 mg dose of rifampicin raised the peak level of venetoclax in the blood (Cmax) by 106% and the total amount of venetoclax in the body over time (AUC) by 78%.
These medicines can affect each other in a serious way. Do not start taking them together unless your doctor has said it is OK. If you already take both, do not stop either one on your own: speak to your doctor or pharmacist soon.