Endosis Dienogest Ketoconazole
ModerateKetoconazole is an antifungal that slows down CYP3A4, an enzyme in the body that helps break down hormone medicines like dienogest. When you take the two together, more dienogest can stay in your blood than usual. This can cause more side effects from dienogest.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.