Doxotor Doxorubicin Hydrochloride Lamivudine + Zidovudine
ModerateTaking Lamivudine + Zidovudine with Doxorubicin can make the side effects of zidovudine worse. Doxorubicin is one of several medicines (along with drugs such as pentamidine, dapsone, co-trimoxazole and vincristine) that can harm the kidneys or lower blood cell counts, and zidovudine is more likely to cause problems when these are used together. The leaflet also says the two can work against each other, so the combination needs a doctor's careful judgement.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.