Defrol OFT Cholecalciferol [Vitamin D3] Phenytoin
ModerateTaking phenytoin together with cholecalciferol [vitamin D3] can reduce the effect of the vitamin D. The text links this to metabolic activation.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.