Quetinil XR 50 Quetiapine Ritonavir
MajorRitonavir strongly inhibits CYP3A4, markedly increasing quetiapine exposure with risk of oversedation, hypotension and QT prolongation.
These medicines can affect each other in a serious way. Do not start taking them together unless your doctor has said it is OK. If you already take both, do not stop either one on your own: speak to your doctor or pharmacist soon.
Clinical management: Reduce quetiapine dose substantially or avoid. Monitor ECG and sedation.