KEZONA Ketoconazole Mefloquine
MajorTaking mefloquine with ketoconazole can raise the risk of a dangerous change in heart rhythm, which means an irregular heartbeat.
These medicines can affect each other in a serious way. Do not start taking them together unless your doctor has said it is OK. If you already take both, do not stop either one on your own: speak to your doctor or pharmacist soon.
What to do: Do not take Mefloquine and Ketoconazole together unless your doctor has said so.