Aresta 40 Enzalutamide Rifampicin
ModerateRifampicin can lower the amount of Enzalutamide in your blood. It also lowers the level of N-desmethyl enzalutamide, the active substance the body makes from Enzalutamide. Rifampicin does this because it speeds up the liver enzymes (CYP3A4, and to a lesser degree CYP2C8) that break these medicines down. With less of the medicine in your body, Enzalutamide may not work as well as it should.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.