Cytograf 1 Capsule Tacrolimus Ketoconazole
MajorLarge increase in tacrolimus levels causing nephrotoxicity and neurotoxicity.
These medicines can affect each other in a serious way. Do not start taking them together unless your doctor has said it is OK. If you already take both, do not stop either one on your own: speak to your doctor or pharmacist soon.
What to do: Monitor tacrolimus trough levels and renal function; reduce dose.