Tolvan 15 Tolvaptan Rifampicin
MajorRifampicin speeds up how the body clears tolvaptan, so the level of tolvaptan in the blood can fall and tolvaptan may work less well. The advice is to avoid taking them together.
These medicines can affect each other in a serious way. Do not start taking them together unless your doctor has said it is OK. If you already take both, do not stop either one on your own: speak to your doctor or pharmacist soon.
What to do: Do not take these together unless your doctor has told you to.