Sutib 25 Sunitinib Rifampicin
ModerateCYP3A4 inducers, such as rifampin, can lower the level of sunitinib in the blood. In a study of healthy volunteers, taking rifampin at the same time as a single dose of sunitinib reduced the combined peak level (Cmax) of sunitinib and its main active metabolite by 23%, and the total exposure (AUC0-∞) by 46%.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.