Ivosenib Ivosidenib Rifampicin
ModerateTaking Rifampicin (rifampin), a strong CYP3A4 inducer, with Ivosidenib is predicted to lower the steady-state AUC of Ivosidenib, which is how much of the medicine stays in your blood, by 33%. This was estimated for 600 mg of Rifampicin once daily for 15 days.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.