Alpesib Alpelisib Warfarin Sodium
ModerateAlpelisib can lower the amount of warfarin in your blood when you take the two together. Warfarin is broken down in the body by an enzyme called CYP2C9, and alpelisib can affect how that enzyme handles it. With less warfarin in the blood, it may not work as well as it should.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.