Carfilez 10 Carfilzomib Midazolam
ModerateClinical studies found that carfilzomib did not change how the body handles midazolam. Midazolam is a sensitive CYP3A substrate, which means the liver enzyme CYP3A breaks it down, and when the two were given together the way midazolam was processed stayed the same.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.