People taking orlistat and levothyroxine together have developed hypothyroidism (an underactive thyroid). If you take both, your thyroid function should be checked for any changes. Take levothyroxine and orlistat at least 4 hours apart.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.
What to do: Ask your doctor or pharmacist. They may check your thyroid. Take levothyroxine and orlistat at least 4 hours apart.