Alkon Capsule Ceritinib Warfarin Sodium
ModerateCeritinib can raise the amount of warfarin in your body, because warfarin is a CYP2C9 substrate, meaning your body breaks it down through the CYP2C9 enzyme, and ceritinib slows that process. This can make warfarin's blood-thinning effect stronger than usual. If you have to take both together, your doctor should check your INR (the blood test that shows how thin your blood is) more often.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.