Brigacent 90 Brigatinib Rifampicin
MajorRifampicin can lower the amount of brigatinib in the blood, and that may make brigatinib work less well. Rifampin, a strong CYP3A inducer, was shown to reduce brigatinib levels in the blood. Because of this, brigatinib should not be taken together with strong CYP3A inducers such as rifampin, carbamazepine, phenytoin and St. John's wort.
These medicines can affect each other in a serious way. Do not start taking them together unless your doctor has said it is OK. If you already take both, do not stop either one on your own: speak to your doctor or pharmacist soon.