Prostaxen Apalutamide Clarithromycin
ModerateWhen you take apalutamide with clarithromycin, which is a strong inhibitor of CYP3A4, no initial dose adjustment is necessary, but a reduction of the apalutamide dose based on tolerability should be considered.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.