Solina-10 Solifenacin Succinate Ketoconazole
ModerateKetoconazole blocks an enzyme that helps your body clear solifenacin, so solifenacin builds up. With ketoconazole 200 mg a day, the amount of solifenacin in your blood doubles. At 400 mg a day, it triples.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.
What to do: Ask your doctor or pharmacist before taking these together. They may check you or change your treatment plan.