ALECTA 150 CAPSULE Alectinib Ketoconazole
ModerateKetoconazole can raise the level of Alectinib in your body, because it slows down the liver enzyme (CYP3A) that helps clear Alectinib. Because of this, your doctor should keep a closer watch on you if you take both together. Grapefruit and Seville oranges can have the same effect, so avoid them unless your doctor says it is fine. Do not stop or change either medicine on your own.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.