Atanib Afatinib Dimaleate Phenobarbital
ModerateAfatinib dimaleate and phenobarbital interact, because phenobarbital is a P-gp inducer. The text doesn't say what the effect of taking them together is.
These medicines are often taken together with some care. Your doctor may change a dose, space them apart or check on you more often. Make sure your doctor and pharmacist know you take both.